![]() ![]() MOLES has been validated in an ocular oncology setting and shows a high sensitivity for indicating malignancy.Ī3 (modified): Probable melanoma.Tumours are diagnosed according to the sum of these five scores as: Each feature is scored 0, 1, or 2 depending on whether they are absent, borderline/uncertain, or present. the MOLES scoring system (see below) scores five features of melanocytic choroidal tumours that are suggestive of malignancy: mushroom shape, orange pigment, large size, enlarging tumour and sub-retinal fluid.vitreous haemorrhage is rare, occurring only if the tumour has perforated the retina.These tumours are aggressive and often extend extra-ocularly by the time of diagnosis with a wide base but minimal thickening). about 5% of choroidal melanomas are diffuse (i.e.If they break through Bruch’s membrane and RPE, they can develop a mushroom (‘collar stud’) shape, which is almost pathognomic for melanoma larger choroidal melanomas are dome-shaped, with more extensive serous retinal detachment.documented growth (which requires sequential colour photography).subretinal fluid, most easily seen on OCT.clumps of orange pigment (which are hyper-autofluorescent).there is a size overlap between choroidal naevi and choroidal melanomas with the following relative frequencies:. ![]()
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